Formulation and Evaluation of Poly Herbal Tablet for Bone Healing
DOI:
https://doi.org/10.54060/a2zjournals.ijahr.43Keywords:
Fracture, Bone healing, Hadjod, Guggul, Babool, Triphala, Ashwagandha, Bone restoration, cell proliferation and differentiation, calcium supplements, anti-inflammatory, analgesics, wound healingAbstract
The present study was designated to formulate and evaluate the poly herbal tablet for bone healing properties. The plants were selected on the basis of their individual properties for restoring fractured bone to its original along with the supporting actions of anti-inflammatory, calcium supplements and others numbers of nutrients and supplements, analgesic, wound healing, anti-arthritic activities for the better and faster reformation of bone. Plants such as hadjod, guggul, babool, triphala and ashwagandha used respectively. Babool helps us giving calcium supplement, guggul increases deposition of calcium towards bone, triphala shows wound healing properties and ashwagandha is used for its analgesic activities. The doses were selected on the basis of referencing material along with the upper and lower limit of usage of dose. The three formulations of varying amount of composition are prepared and evaluation is carried out. The physical evaluation parameters were per-formed for the tablet formulation. The pre as well as post evaluation parameters were observed, and result were calculat-ed, and comparison studies are carried out to find out the optimum formulation.
Downloads
References
Singh V. Medicinal plants and bone healing. Natl J Maxillofac Surg. 2017;8(1):4-11. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5512407/
Science Society. Overview of Indian healing traditions. 2016 Apr. Available from: https://www.ncbs.res.in/HistoryScienceSociety/content/overview-indian-healing-traditions
Kalfas IH. Principles of bone healing. Neurosurg Focus. 2001;10(4). Available from: https://pubmed.ncbi.nlm.nih.gov/16732625/
Panigrahi H. The effect of Abha Guggulu in the clinical management of fractures. Ancient Sci Life. 1997;17(1):3-9. Available from: https://journals.lww.com/asol/abstract/1997/17010/the_effect_of_abha_guggulu_in_the_clinical.1.aspx
Mukherjee T, Saha N, Palbag S. Ethnopharmacology, phytochemistry, and pharmacology of Ayurvedic plant Hadjod-Cissus quadrangularis. Int J Res Ayurveda Pharm. 2016;7(4):78-82. Available from: https://www.researchgate.net/publication/305356131
Mishra G, Shrivastava S, Nagori B. Pharmacological activity and therapeutic activity of Cissus quadrangularis: An over-view. Int J PharmTech Res. 2010;2(2):1298-1310.
Pansare TA, Chandil S. Asthisanharak (Cissus quadrangularis Linn) an Ayurvedic herbal modern perspective. Sch Int J Tradit Complement Med. 2019;2(3):32-8. Available from: https://saudijournals.com/media/articles/SIJTCM-23-32-38-c.pdf
Tomar R, Kaur G, Sannd R, Singh H, Sarkar B. A review on Guggulu formulation used in Ayurveda. Natl Inst Ayurvedic Pharm Res. 2014;3(3-4):96-113. Available from: https://www.researchgate.net/publication/280483161
Kumari S, Srivastava P, Pandey S, Talreja S. A complete pharmacognostic review on Amla. World J Pharm Pharm Sci. 2020;8(4):622-37. Available from: https://www.researchgate.net/publication/343294978
Singh DC, Dhyani S, Kaur G. A critical review on Guggulu [Commiphora wightii (Arn) Bhand] and its miraculous uses. Int J Ayurveda Pharm Res. 2015;3(1). Available from: https://ijapr.in/index.php/ijapr/article/view/168
Gowda DV, Muguli G, Rangesh PR, Deshpande RD. Phytochemical and pharmacological actions of Triphala Ayurvedic formulation. Int J Sci Rev Res. 2012;15(12). Available from: https://www.researchgate.net/publication/234044841
Chouhan B, Kumawat RC, et al. Triphala: A comprehensive Ayurvedic review. Int J Res Ayurveda Pharm. 2013;4(4). Available from: https://www.researchgate.net/publication/269846920
Gupta GL, Rana AC. Plant review Withania somnifera (Ashwagandha). Phcog Rev. 2007;1(1):129-36. Available from: https://scholar.google.com/scholar_lookup?journal=Phcog+Rev&title=PHCOG+MAG.:+plant+review+Withania+somnif-era+(Ashwagandha):+a+review&author=G.L.+Gupta&author=A.C.+Rana&volume=1&publication_year=2007&pages=129-136&
Javed SR, Cristina Q, et al. Chemical composition, biological activity, and health-promoting effects of Withania som-nifera for pharma food industry applications. J Food Ind. 2021.
Kumar V, Saifi T, Gupta G, Anil, et al. Review on Acacia arabica (Babool): Biological, morphological, and pharmacolog-ical studies as well as ethnobotanical, Unani, and traditional uses. Int J Adv Eng Manag. 2022;4(1):1136-44. Available from: https://ijaem.net/issue_dcp/A%20Review%20on%20Acacia%20arabica%20Babool
Tewari A, Singh P. An overview on chemistry and applications of Acacia gums. Scholar Res Libr. 2010;2(3):327-31. Available from: https://www.derpharmachemica.com/pharma-chemica/an-over-view-on-chemistry-and-applications-of-acacia-gums.pdf
Kakadia N, Vegad K, Kanaki N. Acacia arabica (Lam) Wild. on osteoblastogenesis, osteoblast proliferation, osteoclastic activity, and bone calcium mineralization. J Complement Integr Med. 2022;19(3). Available from: https://pubmed.ncbi.nlm.nih.gov/35343656/
Roqaiya M, Begum W, Jahufer R. Acacia arabica (Babool) - A review on ethnobotanical and Unani traditional uses as well as phytochemical and pharmacological properties. Int J Pharm Phytopharmacol Res. 2015;4(6):315-21.
Arora P, Arora V. Preparation of tablet as per pharmacopoeia requirement. In: Textbook of Herbal Drug Technology. PV Prakashan; 2019. p. 193-4.
Mishra US, Murthy PN, Pasa G, Mishra D. Formulation development and evaluation of herbal tablet containing methanolic extract of Butea frondosa. Int J Inst Pharm Life Sci. 2011. Available from: https://journals.innovareacademics.in/index.php/ijap/article/view/30113/16841
Christianah I, Ekere K, Judith O, Olayemi O, Darlington O, et al. Phytopharmaceutical properties of herbal teas circu-lating in the Nigerian market. Afr J Pharm Pharmacol. 2016;10(47):1007-13. Available from: https://www.researchgate.net/publication/313494243
Chavan P, Kalshetti M, Navindgikar N. Formulation and evaluation of herbal tablets containing Nyctanthes ar-bor-tristis leaves. Int J Curr Pharm Res. 2020;12(3). Available from: https://www.researchgate.net/publication/341436126
Panigrahi H. The effect of Abha Guggulu in the clinical management of fractures. Ancient Sci Life. 1997;17(1):3-9. Available from: https://journals.lww.com/asol/abstract/1997/17010/the_effect_of_abha_guggulu_in_the_clinical.1.aspx
Downloads
Published
How to Cite
CITATION COUNT
Issue
Section
License
Copyright (c) 2025 Tanmay Shah; Yukti Rana, Nandini Modi, Rumana Dutiya
This work is licensed under a Creative Commons Attribution 4.0 International License.
